MVT 2163

Drug Profile

MVT 2163

Alternative Names: 89Zr-DFO-HuMab-5B1; 89Zr-HuMab 5B1; anti-sialyl Lewisa imaging agent - MabVax; ImmunoPet imaging agent - MabVax Therapeutics; MVT-2163; radiolabeled HuMab 5B1 antibody; radiolabelled 5B1 antibody; radiolabelled 5B1 diabody; radiolabelled anti-CA 19.9 antibody

Latest Information Update: 07 Oct 2017

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At a glance

  • Originator HonorHealth; MabVax Therapeutics
  • Developer MabVax Therapeutics; Memorial Sloan-Kettering Cancer Center
  • Class Drug conjugates; Imaging agents; Immunoconjugates; Monoclonal antibodies; Monoclonal antibody diagnostics; Radiopharmaceutical diagnostics
  • Mechanism of Action Diagnostic imaging enhancers; Ionising radiation emitters; Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Pancreatic cancer
  • Preclinical Bladder cancer; Colorectal cancer; Small cell lung cancer

Most Recent Events

  • 04 Oct 2017 Pharmacokinetics data from a preclinical study in Pancreatic cancer diagnosis released by MabVax
  • 22 Aug 2017 MabVax completes the phase I trial in Pancreatic cancer (Diagnosis, Late-stage disease, Metastatic disease) in USA, before August 2017
  • 14 Jun 2017 Pharmacokinetics and safety data from a phase I trial in Pancreatic cancer (Diagnosis) released by MabVax
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