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KIO 104

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Drug Profile

KIO 104

Alternative Names: KIO 101; KOI-104; PaniDrop; PaniJect; PP-001 - Panoptes Pharma

Latest Information Update: 28 May 2026

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At a glance

  • Originator 4SC Discovery
  • Developer Kiora Pharmaceuticals; Panoptes Pharma
  • Class Anti-infectives; Anti-inflammatories; Eye disorder therapies; Small molecules
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Uveitis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Dry eyes; Retinal oedema
  • Phase I/II Uveitis
  • Preclinical Proliferative vitreoretinopathy
  • No development reported Conjunctivitis; Infectious conjunctivitis; Keratoconjunctivitis

Most Recent Events

  • 28 May 2026 No recent reports of development identified for preclinical development in Infectious conjunctivitis in Austria (Topical)
  • 28 Sep 2025 No recent reports of development identified for research development in Unspecified in USA (PO)
  • 28 Jun 2025 No recent reports of development identified for preclinical development in Unspecified in Unknown (IV)

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