CZ 48

Drug Profile

CZ 48

Alternative Names: Camptothecin-20-O-Propionate Hydrate; CZ48

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Cao Pharmaceuticals; CHRISTUS Stehlin Foundation for Cancer Research
  • Developer Cao Pharmaceuticals; University of Texas Health Science Center at San Antonio
  • Class Antineoplastics; Camptothecins; Esters; Small molecules
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Lymphoma; Solid tumours

Most Recent Events

  • 13 Oct 2017 Phase-I development is ongoing for Solid tumours and Lymphoma in USA (NCT02575638)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Lymphoma(Late-stage disease) in USA (PO, Capsule)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in USA (PO, Capsule)
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