Uprifosbuvir - Merck

Drug Profile

Uprifosbuvir - Merck

Alternative Names: IDX-21437; MK 3682

Latest Information Update: 22 Mar 2018

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At a glance

  • Originator Idenix Pharmaceuticals
  • Developer Merck & Co
  • Class Antivirals; Uracil nucleotides
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis C

Most Recent Events

  • 01 Mar 2018 Merck completes a phase II trial for Hepatitis C (Combination therapy, Treatment-naive, Treatment experienced) in Spain, Poland and the UK (NCT02956629)
  • 16 Nov 2017 Merck Sharp & Dohme completes the phase II C-BREEZE 1 trial for Hepatitis C (Combination therapy, Treatment naive, Treatment experienced) in USA (PO) (NCT02759315)
  • 20 Oct 2017 Efficacy and adverse events data from the phase II C-BREEZE 1 trial in Hepatitis C infection presented at the 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2017)
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