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Rogaratinib - Bayer

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Drug Profile

Rogaratinib - Bayer

Alternative Names: BAY-1163877

Latest Information Update: 03 Oct 2024

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At a glance

  • Originator Bayer
  • Developer Bayer; Fundacion CRIS de Investigacion para Vencer el Cancer; Swiss Group for Clinical Cancer Research
  • Class Amines; Antineoplastics; Piperazines; Pyrroles; Small molecules; Thiophenes; Triazines
  • Mechanism of Action Type 1 fibroblast growth factor receptor antagonists; Type 3 fibroblast growth factor receptor antagonists; Type 4 fibroblast growth factor receptor antagonists; Type-2 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Urogenital cancer
  • No development reported Breast cancer; Solid tumours
  • Discontinued Non-small cell lung cancer

Most Recent Events

  • 03 Oct 2024 Bayer completes phase-I/II clinical trials in Urogenital cancer (Combination therapy, Late-stage disease, Metastatic disease, First-line therapy) in Austria, Spain, Italy, France, Japan, Germany, South Korea and USA (PO) (NCT03473756)
  • 28 Dec 2023 No recent reports of development identified for phase-I development in Breast-cancer(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Spain (PO)
  • 05 Dec 2023 Efficacy and safety data from the phase I ROGABREAST trial in Breast cancer presented at the 46th Annual San Antonio Breast Cancer Symposium (SABCS-2023)

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