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Mirikizumab - Eli Lilly and Company

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Drug Profile

Mirikizumab - Eli Lilly and Company

Alternative Names: IL-23 antibody - Eli Lilly and Company; IL-23p19 antibody - Eli Lilly and Company; LY 3074828; Miri - Eli Lilly and Company; OMVOH; Omvoh

Latest Information Update: 01 Jun 2026

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At a glance

  • Originator Eli Lilly and Company
  • Class Anti-inflammatories; Antipsoriatics; Monoclonal antibodies; Obesity therapies
  • Mechanism of Action Interleukin-23 subunit p19 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ulcerative colitis; Crohn's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ulcerative colitis
  • Registered Crohn's disease
  • Phase III Obesity
  • Discontinued Plaque psoriasis

Most Recent Events

  • 04 May 2026 Eli Lilly and Company initiates a phase II trial for Crohn's disease (Combination therapy, Treatment-experienced) in the USA (IV, SC) , (NCT07483099)
  • 04 May 2026 Eli Lilly and Company initiates a phase II trial for Ulcerative colitis and Crohn's disease (Combination therapy, Treatment-resistant ) in the USA (IV, SC) , (NCT07483073)
  • 01 May 2026 Eli Lilly and Company completes a phase-III clinical trials in Ulcerative colitis (In adolescents, In children, Treatment-experienced) in the USA, Belgium, Canada, France, Germany, Israel, Italy, Japan, Poland, South Korea and United Kingdom (IV) (SC) (NCT05784246)

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