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Mirikizumab - Eli Lilly and Company

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Drug Profile

Mirikizumab - Eli Lilly and Company

Alternative Names: IL-23 antibody - Eli Lilly and Company; IL-23p19 antibody - Eli Lilly and Company; LY 3074828; Miri - Eli Lilly and Company; OMVOH; Omvoh

Latest Information Update: 05 Nov 2025

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At a glance

  • Originator Eli Lilly and Company
  • Class Anti-inflammatories; Antipsoriatics; Monoclonal antibodies; Obesity therapies
  • Mechanism of Action Interleukin-23 subunit p19 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ulcerative colitis; Crohn's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ulcerative colitis
  • Registered Crohn's disease
  • Phase III Obesity
  • Discontinued Plaque psoriasis

Most Recent Events

  • 27 Oct 2025 Eli Lilly plans to launch single-injection, once-monthly maintenance regimen (200 mg/2 mL) mirikizumab for subcutaneous use in Ulcerative colitis in USA by early 2026
  • 27 Oct 2025 European Medicines Agency approves a single-injection, once-monthly maintenance regimen (200 mg/2 mL) of Mirikizumab for Ulcerative colitis in European union, Iceland, Norway and Lichtenstein before October 2025
  • 27 Oct 2025 US FDA approves a single-injection, once-monthly maintenance regimen (200 mg/2 mL) of Mirikizumab for Ulcerative colitis in USA

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