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Mirikizumab - Eli Lilly and Company

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Drug Profile

Mirikizumab - Eli Lilly and Company

Alternative Names: IL-23 antibody - Eli Lilly and Company; IL-23p19 antibody - Eli Lilly and Company; LY 3074828; Miri - Eli Lilly and Company; OMVOH; Omvoh

Latest Information Update: 18 Dec 2024

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At a glance

  • Originator Eli Lilly and Company
  • Class Anti-inflammatories; Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action Interleukin-23 subunit p19 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ulcerative colitis; Crohn's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ulcerative colitis
  • Preregistration Crohn's disease
  • Discontinued Plaque psoriasis

Most Recent Events

  • 13 Dec 2024 EMA's CHMP adopts a positive opinion, recommending the granting of a marketing authorisation for mirikizumab in Crohn's disease in the European Union
  • 28 Oct 2024 Preregistration for Crohn's disease in Canada (SC)
  • 28 Oct 2024 Mirikizumab has boxed warning for hypersensitivity, increased risk of infection, tuberculosis, hepatotoxicity and immunizations

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