Pamiparib - BeiGene

Drug Profile

Pamiparib - BeiGene

Alternative Names: BeiGene-290; BGB-290; PARPi - BeiGene

Latest Information Update: 26 Jul 2018

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At a glance

  • Originator BeiGene
  • Developer BeiGene; Merck Serono
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase 1 inhibitors; Poly(ADP-ribose) polymerase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Gastric cancer; Ovarian cancer
  • Phase II Breast cancer
  • Phase I/II Glioblastoma; Solid tumours
  • Phase I Fallopian tube cancer; Peritoneal cancer

Most Recent Events

  • 23 May 2018 Phase-II clinical trials in Breast cancer (Metastatic disease, Recurrent, Second-line therapy or greater) in China (PO) (NCT03575065)
  • 17 May 2018 BeiGene initiates enrolment in a phase III trial for Ovarian cancer (Recurrent, Second-line therapy or greater) in China
  • 09 May 2018 BeiGene plans a global phase III trial for Gastric cancer in the second or third quarter of 2018
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