Pamiparib - BeiGene

Drug Profile

Pamiparib - BeiGene

Alternative Names: BeiGene-290; BGB-290; PARPi - BeiGene

Latest Information Update: 20 Apr 2018

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At a glance

  • Originator BeiGene
  • Developer BeiGene; Merck Serono
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase 1 inhibitors; Poly(ADP-ribose) polymerase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Ovarian cancer
  • Phase I/II Glioblastoma; Solid tumours
  • Phase I Breast cancer; Fallopian tube cancer; Peritoneal cancer

Most Recent Events

  • 16 Apr 2018 Safety and efficacy data of phase I trial of pamiparib presented at American Association for Cancer Research Annual Meeting 2018 (AACR-2018)
  • 28 Feb 2018 BeiGene plans a global phase III trial for Gastric cancer in 2018
  • 09 Feb 2018 BeiGene plans a phase III trial for Gastric Cancer (First-line therapy; Late-stage disease) in USA , (NCT03427814)
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