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Pamiparib - BeiGene

Drug Profile

Pamiparib - BeiGene

Alternative Names: BeiGene-290; BGB-290; BGB-290-BeiGene; PARPi - BeiGene

Latest Information Update: 05 Feb 2020

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At a glance

  • Originator BeiGene
  • Developer BeiGene; Merck Serono; National Cancer Institute (USA); Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase 1 inhibitors; Poly(ADP-ribose) polymerase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Cancer; Fallopian tube cancer; Gastric cancer; Ovarian cancer
  • Phase II Breast cancer; Prostate cancer
  • Phase I/II Glioblastoma; Glioma; Solid tumours
  • No development reported Peritoneal cancer

Most Recent Events

  • 03 Jan 2020 Phase-I/II clinical trials in Glioma (Recurrent, Late-stage disease, Second-line therapy or greater, Combination therapy) in USA (PO) (NCT03914742)
  • 28 Dec 2019 No recent reports of development identified for phase-I development in Fallopian-tube-cancer(Metastatic disease, Recurrent, Second-line therapy or greater) in China (PO)
  • 28 Dec 2019 No recent reports of development identified for phase-I development in Peritoneal-cancer(Metastatic disease, Recurrent, Second-line therapy or greater) in China (PO)
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