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Lifirafenib - BeOne Medicines

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Drug Profile

Lifirafenib - BeOne Medicines

Alternative Names: BeiGene 283; BGB 283; BGB-283-sesqui-maleate; Lifirafenib maleate

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator BeiGene
  • Developer BeOne Medicines; SpringWorks Therapeutics
  • Class Antineoplastics; Benzimidazoles; Benzofurans; Cyclopropanes; Naphthyridines; Small molecules
  • Mechanism of Action Proto-oncogene protein b-raf inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 01 Jul 2025 SpringWorks Therapeutics has been acquired by Merck KGaA
  • 28 Sep 2023 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia (PO)
  • 28 Sep 2023 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)

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