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Gimeracil/oteracil/tegafur/folinic acid - Taiho Pharmaceuticals

Drug Profile

Gimeracil/oteracil/tegafur/folinic acid - Taiho Pharmaceuticals

Alternative Names: Folinic acid/S-1; Gimeracil/oteracil potassium/tegafur/calcium folinate; Gimeracil/oteracil potassium/tegafur/folinic acid; Gimeracil/oteracil/tegafur/calcium folinate; Gimeracil/oteracil/tegafur/leucovorin; S-1/folinic acid; TAS 118

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Taiho Pharmaceutical
  • Class Antineoplastics; Chemoprotectants; Chemosensitisers; Formyltetrahydrofolates; Furans; Pyridines; Pyrimidinones; Small molecules; Triazines; Vitamins
  • Mechanism of Action Antimetabolites; DNA synthesis inhibitors; Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Gastric cancer; Pancreatic cancer; Solid tumours

Most Recent Events

  • 26 Aug 2020 Discontinued - Phase-I for Solid tumours in Japan (PO) (Otsuka pharmaceuticals pipeline June 2020)
  • 26 Aug 2020 Discontinued - Phase-III for Gastric cancer (Combination therapy, First-line therapy, Late-stage disease) in South Korea, Japan (PO) (Otsuka pharmaceuticals pipeline June 2020)
  • 26 Aug 2020 Discontinued - Phase-III for Pancreatic cancer (Refractory metastatic disease) in Japan, South Korea (PO) (Otsuka pharmaceuticals pipeline June 2020)
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