Nogapendekin alfa inbakicept - Altor BioScience Corporation
Alternative Names: ALT 803; ANKTIVA; IL-15N72D/IL-15Ra-Fc - Altor BioScience Corporation; IL-15N72D:IL-15RαSu/Fc fusion protein complex; IL-15sa - Altor BioScience Corporation; Interleukin 15 superagonist - Altor BioScience Corporation; N-803; Nogapendekin alfa inbakicept - ImmunityBio; Nogapendekin alfa inbakicept-pmln - Altor BioScience Corporation; Superagonist Interleukin-15:Interleukin-15 receptor alphaSu/Fc Fusion complex - Altor BioScience Corporation; VesAnktiva™Latest Information Update: 15 Sep 2025
At a glance
- Originator Altor BioScience Corporation
- Developer Altor BioScience Corporation; ImmunityBio; National Cancer Institute (USA)
- Class Antineoplastics; Antiretrovirals; Immunoglobulin Fc fragments; Immunotherapies; Interleukins; Recombinant fusion proteins
- Mechanism of Action Interleukin 15 receptor agonists
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Bladder cancer
- Registered Lymphopenia
- Phase III Non-small cell lung cancer
- Phase II Acute myeloid leukaemia; Cervical cancer; Colorectal cancer; Fallopian tube cancer; Gastric cancer; Glioblastoma; Hereditary nonpolyposis colorectal cancer; HIV infections; Liver cancer; Malignant melanoma; Merkel cell carcinoma; Myelodysplastic syndromes; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Post acute COVID 19 syndrome; Renal cell carcinoma; Small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
- Phase I/II Endometrial cancer; Multiple myeloma; Non-Hodgkin's lymphoma; Prostate cancer; Triple negative breast cancer
- Phase I Cancer
- No development reported COVID 2019 infections; HIV-1 infections
Most Recent Events
- 08 Sep 2025 Updated efficacy data from the phase II QUILT-3.055 trial in Non-small cell cancer released by a ImmunityBio
- 27 Aug 2025 Interim efficacy data from a phase II trial in Glioblastoma released by ImmunityBio
- 27 Aug 2025 ImmunityBio plans a phase II trial for Glioblastoma (Secon-line therapy or greater)