Ilodecakin - ARMO Biosciences

Drug Profile

Ilodecakin - ARMO Biosciences

Alternative Names: AM 0010; LY-3500518; PEG-ilodecakin; PEG-rHuIL-10; Pegilodecakin; PEGylated Human IL-10; PEGylated Interleukin-10; PEGylated recombinant human Interleukin-10

Latest Information Update: 30 Jul 2018

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At a glance

  • Originator Merck & Co
  • Developer ARMO Biosciences
  • Class Anti-inflammatories; Antineoplastics; Immunotherapies; Interleukins; Polyethylene glycols
  • Mechanism of Action Interleukin-10 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Pancreatic cancer
  • Phase II Non-small cell lung cancer
  • Phase I Breast cancer; Colorectal cancer; Malignant melanoma; Ovarian cancer; Prostate cancer; Renal cell carcinoma
  • Discontinued Fibrosis; Hypercholesterolaemia; Inflammatory bowel diseases

Most Recent Events

  • 30 Jul 2018 Discontinued - Preclinical for Fibrosis in USA (SC) (Eli Lilly pipeline, July 2018)
  • 30 Jul 2018 Discontinued - Preclinical for Hypercholesterolaemia in USA (SC) (Eli Lilly pipeline, July 2018)
  • 30 Jul 2018 Discontinued - Preclinical for Inflammatory bowel disease in USA (SC) (Eli Lilly pipeline, July 2018)
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