DSM 265

Drug Profile

DSM 265

Alternative Names: DSM-265; PfSPZ

Latest Information Update: 19 May 2017

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At a glance

  • Originator Monash University; University of Texas Southwestern Medical Center; University of Washington
  • Developer Center for Infectious Disease Research; Fred Hutchinson Cancer Research Center; Medicines for Malaria Venture; Takeda; United States Department of Defense
  • Class Antimalarials; Pyrimidines; Small molecules; Triazoles
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Malaria

Most Recent Events

  • 19 May 2017 Medicines for Malaria Venture plans a phase I trial in Healthy volunteers in Australia (ACTRN12617000711314)
  • 13 Sep 2016 Medicines for Malaria Venture and AbbVie terminate a phase I bioavailability trial in Healthy volunteers in USA (PO, Granule) (NCT02750384)
  • 01 May 2016 Medicines for Malaria Venture and AbbVie initiate a phase I bioavailability trial in Healthy volunteers in USA (PO, Granule) (NCT02750384)
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