Fenebrutinib - Genentech

Drug Profile

Fenebrutinib - Genentech

Alternative Names: GDC-0853; RG 7845; RO 7010939

Latest Information Update: 10 Oct 2018

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At a glance

  • Originator Genentech
  • Developer Chugai Pharmaceutical; Genentech
  • Class Antineoplastics; Antirheumatics; Piperazines; Pyrazines; Pyridines
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Rheumatoid arthritis; Systemic lupus erythematosus; Urticaria
  • Phase I Autoimmune disorders
  • Discontinued Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 08 Oct 2018 Genentech plans a phase II trial for Urticaria in USA, Canada and Germany , (NCT03693625)
  • 23 Aug 2018 Roche completes a phase I trial in Healthy volunteers in USA (PO) (NCT03596632)
  • 27 Jul 2018 Roche initiates a phase I trial in Healthy volunteers in USA (PO) (NCT03596632)
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