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Bepirovirsen - GSK

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Drug Profile

Bepirovirsen - GSK

Alternative Names: 3228836; Bepirovirsen sodium; GSK'836; GSK-4388067; GSK-4388067A; GSK3228836; GSK3228836A; GSK3228836B; IONIS-HBVRx; ISIS 505358; ISIS-GSK3Rx; ISIS-HBVRx

Latest Information Update: 16 Nov 2024

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer GSK; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides; Antivirals
  • Mechanism of Action Hepatitis B surface antigen expression inhibitors; RNA interference; Toll-like receptor 8 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hepatitis B

Most Recent Events

  • 30 Oct 2024 Bepirovirsen receives SENKU designation in Japan for chronic hepatitis B
  • 17 Sep 2024 GlaxoSmithKline initiates the phase II B-Focus trial for Hepatitis B in USA (NCT06497504)
  • 11 Jul 2024 GlaxoSmithKline plans the phase II B-Focus trial for Hepatitis B in USA, in September 2024 (NCT06497504)

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