Tenalisib - Rhizen Pharmaceuticals

Drug Profile

Tenalisib - Rhizen Pharmaceuticals

Alternative Names: RP 6530

Latest Information Update: 19 Jun 2018

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At a glance

  • Originator Rhizen Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors; Phosphatidylinositol 3 kinase gamma inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T cell lymphoma; Peripheral T-cell lymphoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Hodgkin's disease
  • Phase I Cutaneous T cell lymphoma; Haematological malignancies; Peripheral T-cell lymphoma
  • Preclinical Ovarian cancer

Most Recent Events

  • 01 Jun 2018 Updated efficacy and safety data from a phase I/Ib trial in T-cell lymphoma presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 29 May 2018 Phase-I/II clinical trials in Hodgkin's disease (Second-line therapy or greater) in USA (PO) (NCT03471351)
  • 29 May 2018 Rhizen Pharmaceuticals plans a phase II trial in indolent Non-Hodgkin lymphoma (Second-line therapy or greater, Monotherapy)
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