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TAK 114

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Drug Profile

TAK 114

Alternative Names: Meisoindigo; Natura-α; TAK-114

Latest Information Update: 23 May 2016

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At a glance

  • Originator Natrogen Therapeutics International
  • Developer Natrogen Therapeutics International; Takeda Pharmaceuticals International GmbH
  • Class Anti-inflammatories; Indoles; Small molecules
  • Mechanism of Action Cytokine modulators; Regulatory T-lymphocyte modulators; STAT3 transcription factor inhibitors; Th17 cell modulators; Transcription factor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Prostate cancer; Systemic lupus erythematosus; Ulcerative colitis

Most Recent Events

  • 10 May 2016 Discontinued - Phase-I for Ulcerative colitis in Japan (PO)
  • 10 May 2016 Discontinued - Phase-II for Ulcerative colitis in European Union, USA (PO)
  • 30 Nov 2014 Takeda initiates enrolment in a phase I trial in volunteers in Japan (NCT02286518)

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