INCB 50465

Drug Profile

INCB 50465

Alternative Names: INCB-050465; INCB-50465

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Incyte Corporation
  • Class Antineoplastics
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal-zone-B-cell-lymphoma; Myelofibrosis
  • Phase I/II B cell lymphoma; Solid tumours

Most Recent Events

  • 09 Feb 2018 Incyte Corporation plans the phase I CITADEL-112 trial for B-cell lymphoma in USA in June 2018 (NCT03424122)
  • 09 Dec 2017 Updated efficacy and adverse events data from the phase I/II CITADEL-101 trial in B-cell lymphoma presented at the 59th Annual Meeting and Exposition of the American Society of Hematology (ASH-2017)
  • 25 Oct 2017 Incyte Corporation plans the phase I CITADEL-111 trial for B-cell lymphoma (Second-line therapy or greater) in June 2018 (NCT03314922)
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