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Parsaclisib - Incyte Corporation

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Drug Profile

Parsaclisib - Incyte Corporation

Alternative Names: IBI-376; INCB-050465; INCB-50465

Latest Information Update: 15 Jan 2020

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At a glance

  • Originator Incyte Corporation
  • Developer Incyte Corporation; Innovent Biologics
  • Class Antineoplastics; Pyrazoles; Pyrimidines; Pyrrolidines
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Autoimmune haemolytic anaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Myelofibrosis; Sjogren's syndrome
  • Phase I/II B-cell lymphoma; Haematological malignancies; Solid tumours
  • Preclinical Cancer; Systemic lupus erythematosus

Most Recent Events

  • 13 Jan 2020 MorphoSys and Incyte Corporation plan a clinical trial in B-cell malignancies (Combination therapy, Second-line therapy or greater)
  • 29 Oct 2019 UNC Lineberger Comprehensive Cancer Center and Incyte Corporation plans a phase I trial for Breast cancer (Monotherapy) (PO) (NCT04142554)
  • 28 Aug 2019 Innovent Biologics files an IND application with the NMPA in China, before August 2019
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