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Meropenem/vaborbactam - Melinta Therapeutics

Drug Profile

Meropenem/vaborbactam - Melinta Therapeutics

Alternative Names: Carbavance™; Meropenem and vaborbactam; Meropenem trihydrate/vaborbactam; Meropenem/RPX-7009; RPX-2014/RPX-7009; RPX-7009/RPX-2014; Vabomere; Vaborem

Latest Information Update: 12 Jul 2023

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At a glance

  • Originator Rempex Pharmaceuticals
  • Developer Melinta Therapeutics; Menarini; Rempex Pharmaceuticals; US Department of Health and Human Services
  • Class Antibacterials; Pyrrolidines; Small molecules; Thienamycins
  • Mechanism of Action Beta lactamase inhibitors; Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Bacteraemia; Bacterial infections; Gram-negative infections; Intra-abdominal infections; Nosocomial pneumonia; Pyelonephritis; Urinary tract infections; Ventilator associated pneumonia
  • Phase III Pneumonia

Most Recent Events

  • 10 Jul 2023 Melinta Therapeutics receives BARDA grant for meropenem/vaborbactam development in Chronic urinary tract infections
  • 10 Jul 2023 Melinta Therapeutics plans to submit sNDA for chronic urinary tract infections (In adolescents, In children) and Sepsis (In neonates)
  • 15 May 2023 Oritavancin licensed to Xediton Pharmaceuticals in Canada
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