Meropenem/vaborbactam - Melinta Therapeutics

Drug Profile

Meropenem/vaborbactam - Melinta Therapeutics

Alternative Names: Carbavance™; Meropenem and vaborbactam; Meropenem/RPX-7009; RPX-2014/RPX-7009; RPX-7009/RPX-2014; Vabomere

Latest Information Update: 03 May 2018

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At a glance

  • Originator Rempex Pharmaceuticals
  • Developer Melinta Therapeutics; US Department of Health and Human Services
  • Class Antibacterials; Pyrrolidines; Small molecules; Thienamycins
  • Mechanism of Action Beta lactamase inhibitors; Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Urinary tract infections
  • Phase III Bacteraemia; Gram-negative infections; Pneumonia; Pyelonephritis

Most Recent Events

  • 23 Apr 2018 Additional safety and efficacy data from the phase III TANGO 2 trial presented at the Annual Meeting of the the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2018)
  • 21 Apr 2018 Pharmacokinetics data from an ex vivo study presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2018)
  • 08 Jan 2018 Melinta Therapeutics acquires Meropenem/Vaborbactam from The Medicines Company
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