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Research programme: TGF-beta antisense oligonucleotides - Isarna Therapeutics

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Drug Profile

Research programme: TGF-beta antisense oligonucleotides - Isarna Therapeutics

Alternative Names: ASPH-0047; ASPH-1047; ASPH-1106; ISTH0047

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Isarna Therapeutics
  • Class Antifibrotics; Antiglaucomas; Antineoplastics; Antisense oligonucleotides; Hepatoprotectants
  • Mechanism of Action Left right determination factor inhibitors; Transforming growth factor beta1 inhibitors; Transforming growth factor beta2 inhibitors; Transforming growth factor beta3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Non-alcoholic steatohepatitis
  • No development reported Cancer; Fibrosis; Glaucoma

Most Recent Events

  • 28 Mar 2025 No recent reports of development identified for preclinical development in Cancer in Germany (Parenteral)
  • 28 Mar 2025 No recent reports of development identified for preclinical development in Fibrosis in Germany (Parenteral)
  • 28 Mar 2025 No recent reports of development identified for preclinical development in Glaucoma in Germany (Parenteral)

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