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Allopurinol/lesinurad - AstraZeneca

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Drug Profile

Allopurinol/lesinurad - AstraZeneca

Alternative Names: DUZALLO; Lesinurad allopurinol FDC; Lesinurad/allopurinol; lesinurad/allopurinol 200/300 FDC; RDEA-594/allopurinol; Zurampic/Allopurinol FDC

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Ardea Biosciences
  • Developer Ardea Biosciences; Grunenthal
  • Class Acetic acids; Antigouts; Cyclopropanes; Naphthalenes; Purines; Small molecules; Sulfides; Triazoles; Urologics
  • Mechanism of Action SLC22A12 protein inhibitors; Xanthine oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Gout; Hyperuricaemia

Most Recent Events

  • 31 Jan 2021 Withdrawn for Gout in USA (PO)
  • 31 Jan 2021 Withdrawn for Hyperuricaemia in USA (PO)
  • 28 Sep 2020 No recent reports of development identified for phase-I development in Gout(In volunteers) in Brazil (PO, Tablet)

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