Allopurinol/lesinurad - AstraZeneca

Drug Profile

Allopurinol/lesinurad - AstraZeneca

Alternative Names: DUZALLO; Lesinurad allopurinol FDC; Lesinurad/allopurinol; lesinurad/allopurinol 200/300 FDC; RDEA-594/allopurinol; Zurampic/Allopurinol FDC

Latest Information Update: 13 Aug 2018

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At a glance

  • Originator Ardea Biosciences
  • Developer Ardea Biosciences; Grunenthal
  • Class Acetic acids; Antigouts; Cyclopropanes; Naphthalenes; Purines; Small molecules; Sulfides; Triazoles; Urologics
  • Mechanism of Action SLC22A12 protein inhibitors; Xanthine oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gout

Most Recent Events

  • 06 Aug 2018 Ironwood Pharmaceuticals issues a notice of termination of the license agreement in USA
  • 29 Jun 2018 The Committee for Medicinal Products for Human Use (CHMP) recommends approval of allopurinol/lesinurad for treatment of Gout in European Union
  • 31 Oct 2017 Launched for Gout in USA (PO)
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