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Sulforafan alfadex - Evgen

Drug Profile

Sulforafan alfadex - Evgen

Alternative Names: Broccoli-sprout-extract; SFX-01; Stabilised sulforaphane; Sulforadex; Sulforafan-alpha-cyclodextrin; Sulforaphane; Sulforaphane-alpha-cyclodextrin; Sulphoraphane-alfadex

Latest Information Update: 06 Nov 2020

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At a glance

  • Originator Lalilab
  • Developer Evgen Pharma
  • Class Antihaemorrhagics; Antineoplastics; Chemopreventatives; Phytotherapies
  • Mechanism of Action Androgen receptor antagonists; Hedgehog protein modulators; Histone deacetylase inhibitors; NF E2 related factor 2 stimulants; Wnt signalling pathway modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II/III SARS-CoV-2 acute respiratory disease
  • Phase II Breast cancer; Subarachnoid haemorrhage
  • No development reported Cardiovascular disorders; Chronic obstructive pulmonary disease; Leukaemia; Multiple sclerosis

Most Recent Events

  • 28 Oct 2020 No recent reports of development identified for preclinical development in Multiple-sclerosis in United Kingdom (PO)
  • 08 Oct 2020 Phase-II/III clinical trials in SARS-COV-2 acute respiratory disease (In adults, In the elderly) in United Kingdom (PO, Capsule) (EudraCT2020-003486-19)
  • 17 Jun 2020 Evgen Pharma plans a phase II/III trial in Acute respiratory distress syndrome associated with COVID-19 in United Kingdom (PO) in July 2020 (EudraCT2020-003486-19)
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