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Research programme: kinase modulators - Blueprint Medicines

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Drug Profile

Research programme: kinase modulators - Blueprint Medicines

Alternative Names: BLU 6864; BLU 9931; c-KIT D816V inhibitor - Blueprint Medicines; Fibroblast growth factor receptor 4 (FGFR4) selective inhibitor - Blueprint Medicines; Highly selective kinase drugs for specific genomically-defined cancer patients - Blueprint Medicines; Kinase inhibitors - Blueprint Medicines; KIT D816V selective inhibitor - Blueprint Medicines; NTRK inhibitors; Phosphotransferase inhibitors - Blueprint Medicines; PRKACA inhibitors - Blueprint Medicines; Protein kinase cAMP-activated catalytic subunit alpha (PRKACA) fusions inhibitors; RET fusion inhibitors - Blueprint Medicines; RET inhibitors - Blueprint Medicines; TrkA inhibitors; Type 4 fibroblast growth factor receptor (FGFR4) antagonists - Blueprint Medicines

Latest Information Update: 28 Dec 2019

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At a glance

  • Originator Blueprint Medicines
  • Class Small molecules
  • Mechanism of Action Advanced glycosylation end product modulators; Fusion oncogene protein inhibitors; Phosphotransferase inhibitors; Protein kinase inhibitors; Protein kinase modulators; Proto-oncogene protein c-kit inhibitors; Receptor protein-tyrosine kinase antagonists; TrkA receptor antagonists; Type 4 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer; Gastrointestinal stromal tumours; Inborn genetic disorders; Liver cancer; Mastocytosis

Most Recent Events

  • 28 Dec 2019 No recent reports of development identified for preclinical development in Cancer in USA
  • 28 Apr 2019 No recent reports of development identified for research development in Inborn genetic disorders in USA
  • 28 Oct 2018 No recent reports of development identified for preclinical development in Gastrointestinal-stromal-tumours in USA

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