BI 1181181

Drug Profile

BI 1181181

Alternative Names: BI-1181181; VTP-37948

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Boehringer Ingelheim; Vitae Pharmaceuticals
  • Developer Boehringer Ingelheim
  • Class Nootropics; Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors; BACE1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease

Most Recent Events

  • 07 Apr 2015 Discontinued - Phase-I for Alzheimer's disease (In volunteers) in Belgium (PO)
  • 01 Apr 2015 Discontinued - Phase-I for Alzheimer's disease (In the elderly, In volunteers, In adults) in Germany (PO)
  • 01 Apr 2015 Boehringer Ingelheim terminates a phase I trial for Alzheimer's disease (In volunteers, In adults, In the elderly) in Germany (NCT02254161)
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