Research programme: antibody therapeutics - F-star

Drug Profile

Research programme: antibody therapeutics - F-star

Alternative Names: Fcab - F-star; Fcab antibody fragments - F-star; FS 101; FS 117; FS 120; FS 17; FS 18; FS 20; FS 22; mAb²TM

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator f-star
  • Class Antineoplastics; Bispecific antibodies; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; CD223 antigen inhibitors; Checkpoint kinase inhibitors; Epidermal growth factor inhibitors; ERBB 2 receptor antagonists; Hepatocyte growth factor inhibitors; Programmed cell death-1 ligand-1inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 05 Mar 2018 F-star Delta Limited plans a phase I trial for solid tumours and haematological malignancies (Late stage disease, Second line therapy or greater, Metastatic disease. Inoperable/unresectable), in April 2018 (NCT03440437)
  • 09 Oct 2017 Heidelberg Pharma is now called Heidelberg Pharma Research
  • 05 Aug 2016 F-star and Ligand Pharmaceuticals enter into an agreement to discover human mono and bi-specific antibodies utilising Ligand's OmniAb platform, before August 2015
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