Drug Profile

TRV 734

Alternative Names: TRV-734

Latest Information Update: 28 Apr 2026

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At a glance

Originator Trevena
Class Analgesics; Drug withdrawal therapies; Small molecules
Mechanism of Action Beta-arrestin inhibitors; Opioid mu receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I Opioid-related disorders
Discontinued Pain

Most Recent Events

28 Apr 2026 TRV 734 is still in phase I trials for Opioid related disorders in USA (PO) (Trevena pipeline, Aril 2026)
28 Mar 2025 No recent reports of development identified for phase-I development in Opioid-related-disorders in USA (PO)
14 Feb 2025 National Institute on Drug Abuse completes a phase I trial in Opioid-related disorders in USA (PO) (NCT04316559)

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