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VCN 01

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Drug Profile

VCN 01

Alternative Names: VCN-01

Latest Information Update: 10 Apr 2025

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At a glance

  • Originator VCN Biosciences
  • Developer AstraZeneca; Theriva Biologics; VCN Biosciences
  • Class Antineoplastics; Eye disorder therapies; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Hyaluronidase stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adenocarcinoma; Retinoblastoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Adenocarcinoma
  • Phase I/II Pancreatic cancer; Retinoblastoma; Squamous cell cancer
  • No development reported Brain cancer; Ovarian cancer; Solid tumours

Most Recent Events

  • 31 Mar 2025 Theriva Biologics plans an End-of-phase II meeting with the US FDA and EMA for the phase III trial for Adenocarcinoma (Metastatic disease) before the end of 2025
  • 31 Mar 2025 Adverse event data from the phase IIb VIRAGE trial for Adenocarcinoma released by Theriva Biologics
  • 28 Mar 2025 No recent reports of development identified for phase-I development in Ovarian-cancer(Combination therapy, Late-stage disease, Second-line therapy or greater) in USA (IV, Injection)

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