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Cabamiquine - Merck Serono

Drug Profile

Cabamiquine - Merck Serono

Alternative Names: DDD-107498; DDD498; GTPL9737; M-5717; MM5717; MMV-121

Latest Information Update: 10 Feb 2025

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At a glance

  • Originator Medicines for Malaria Venture; University of Dundee
  • Developer Merck Serono
  • Class Amides; Antimalarials; Fluorinated hydrocarbons; Morpholines; Pyrrolidines; Quinolines; Small molecules
  • Mechanism of Action Peptide elongation factor 2 inhibitors; Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Falciparum malaria
  • No development reported Malaria

Most Recent Events

  • 12 Dec 2024 Merck KGaA completes a phase IIa CAPTURE 2 trial in Falciparum malaria (Combination therapy, In adolescents, In adults) in Burkina Faso, Gambia, Kenya, Zambia (PO, Capsule) (NCT05974267)
  • 28 May 2024 Merck KGaA completes a phase IIa CAPTURE 1 trial for Falciparum malaria (Combination therapy, In Adolescents, In children, In adults) (PO, Granules) in Burkina Faso, Gabon, Mozambique, Uganda (NCT05689047)
  • 28 Nov 2023 Phase-II clinical trials in Falciparum malaria (Combination therapy, In adolescents, In adults) in Kenya, Burkina Faso, Gambia, Zambia (PO) (NCT05974267)

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