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SIL 204

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Drug Profile

SIL 204

Alternative Names: KRASG12D-LODER; siG12D-LODER; SIL-204

Latest Information Update: 23 Dec 2024

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At a glance

  • Originator Silenseed
  • Developer Silexion Therapeutics
  • Class Antineoplastics; Gene therapies
  • Mechanism of Action KRAS protein modulators; Ras gene modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Pancreatic cancer
  • Research Colorectal cancer

Most Recent Events

  • 17 Dec 2024 Silexion Therapeutics enters into a collaboration with Evonik on advanced siRNA Formulation Development
  • 03 Oct 2024 Pharmacodynamics data from a preclinical trial in Pancreatic cancer released by Silexion Therapeutics
  • 01 Oct 2024 Silexion Therapeutics plans a toxicological studies for SIL 204 in upcoming months in 2024

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