Research programme: mannose receptor-targeted diagnostic and therapeutic agents - Macrophage Therapeutics

Drug Profile

Research programme: mannose receptor-targeted diagnostic and therapeutic agents - Macrophage Therapeutics

Alternative Names: CD206 receptor-targeted diagnostics - Navidea Biopharmaceuticals; Cy3-Manocept; Cy3-Manocept-doxorubicin; Cy3-tilmanocept; Manocept™-derived diagnostic agents - Navidea Biopharmaceuticals; MT 1000; MT 1001; MT 2000; MT 2001; MT 2002; MT-1002

Latest Information Update: 16 Aug 2018

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At a glance

  • Originator Navidea Biopharmaceuticals
  • Developer Macrophage Therapeutics; Navidea Biopharmaceuticals; University of California at San Francisco; Unknown
  • Class Anti-infectives; Anti-inflammatories; Antineoplastics; Antirheumatics; Antituberculars; Cardiovascular therapies; Diagnostic agents; Imaging agents; Immunotherapies; Neuroprotectants; Steroids
  • Mechanism of Action Diagnostic imaging enhancers; Mannose receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Clinical Phase Unknown CNS disorders
  • Preclinical Autoimmune disorders; Cancer; Cardiovascular disorders; Infections; Kaposi's sarcoma; Non-alcoholic fatty liver disease; Rheumatoid arthritis; Tuberculosis
  • Research Crohn's disease; Inflammatory bowel diseases

Most Recent Events

  • 08 Aug 2018 Preclinical development is ongoing in USA for Kaposi's sarcoma, Tuberculosis and Rheumatoid-arthritis (Diagnosis)
  • 08 Aug 2018 Preclinical trials in Kaposi's sarcoma, Tuberculosis and Rheumatoid-arthritis (Diagnosis) in USA (IV, Injection)
  • 29 Mar 2017 Early research in Crohn's disease in USA (unspecified route)
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