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LJPC 401

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Drug Profile

LJPC 401

Alternative Names: LJPC-401; Synthetic human hepcidin - La Jolla Pharmaceutical

Latest Information Update: 25 Aug 2022

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At a glance

  • Originator INSERM
  • Developer La Jolla Pharmaceutical Company
  • Class Anti-infectives; Antianaemics; Antimicrobial cationic peptides; Peptide hormones; Peptides; Proteins
  • Mechanism of Action Biological transport modulators; Hepcidin replacements; Hormone replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia; Beta-thalassaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haemochromatosis; Iron overload

Most Recent Events

  • 22 Aug 2022 La Jolla Pharmaceutical Company has been acquired by Innoviva
  • 29 Jul 2021 La Jolla Pharmaceutical Company terminates a phase II trial in Iron overload in Australia, USA, United Kingdom, Italy, Greece, Cyprus, Lebanon, Thailand, Turkey due to lack of efficacy determined in interim efficacy (NCT03381833)
  • 25 Nov 2019 Updated efficacy data from a phase II trial in Hereditary hemochromatosis released by La Jolla Pharmaceutical

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