LJPC 401

Drug Profile

LJPC 401

Alternative Names: LJPC-401; Synthetic human hepcidin - La Jolla Pharmaceutical

Latest Information Update: 28 Jul 2018

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At a glance

  • Originator INSERM
  • Developer INSERM; La Jolla Pharmaceutical Company
  • Class Anti-infectives; Antianaemics; Antimicrobial cationic peptides; Peptide hormones; Peptides; Proteins
  • Mechanism of Action Hepcidin-replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia; Beta-thalassaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haemochromatosis
  • Phase I Iron overload

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for preclinical development in Iron-overload in France (Parenteral, Injection)
  • 14 Jul 2018 Efficacy, adverse events, pharmacokinetics and immunogenicity data from the phase I trial in Iron-overload presented at the 23rd Congress of the European Haematology Association (EHA-2018)
  • 14 Jun 2018 Updated Efficacy and adverse events and pharmacokinetics data from a phase I trial in Iron-overload presented at the 23rd Congress of the European Haematology Association (EHA-2018)
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