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Cimlanod - Bristol-Myers Squibb

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Drug Profile

Cimlanod - Bristol-Myers Squibb

Alternative Names: BMS-986231; BMS-986231-01; Cimlanod; CXL 1427; HNO Donor; HNO Nitroxyl Donor

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Cardioxyl Pharmaceuticals
  • Developer Bristol-Myers Squibb
  • Class Heart failure therapies; Sulfonamides
  • Mechanism of Action Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Decompensated heart failure; Heart failure

Most Recent Events

  • 28 Jun 2021 No recent reports of development identified for phase-I development in Decompensated-heart-failure(In volunteers) in Hungary (IV, Infusion)
  • 28 Mar 2020 Efficacy data from a phase II trial in Heart failure presented at 2020 Annual Scientific Session of the American College of Cardiology and World Congress of Cardiology (ACC-WCC-2020)
  • 09 Jan 2020 Bristol-Myers Squibb completes a phase II trial for Heart Failure in United Kingdom (NCT03730961)

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