Seltorexant - Janssen Research & Development/Minerva Neurosciences
Alternative Names: JNJ-42847922; JNJ-7922; MIN-202Latest Information Update: 23 Aug 2024
At a glance
- Originator Janssen Research & Development
- Developer Janssen Research & Development; Minerva Neurosciences
- Class Antidepressants; Fluorinated hydrocarbons; Ketones; Pyrimidines; Pyrroles; Sleep disorder therapies; Small molecules; Triazoles
- Mechanism of Action Orexin receptor type 2 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Major depressive disorder
- Phase II Alzheimer's disease; Insomnia
- No development reported Sleep apnoea syndrome
Most Recent Events
- 25 Jul 2024 Janssen Research & Development initiates a phase III trial for Major depressive disorder (Adjunctive treatment, Treatment-experienced) in USA (PO) (NCT06559306) ( EudraCT2023-509070-36-00)
- 29 May 2024 Efficacy and adverse event data from a phase III trial in Major depressive disorder released by Johnson & Johnson
- 28 May 2024 No recent reports of development identified for phase-I development in Major depressive disorder(Adjunctive treatment) in Germany (PO, Tablet)