Seltorexant - Janssen Pharmaceuticals/Minerva Neurosciences

Drug Profile

Seltorexant - Janssen Pharmaceuticals/Minerva Neurosciences

Alternative Names: JNJ-42847922; JNJ-7922; MIN-202

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator Janssen Research & Development
  • Developer Janssen Research & Development; Minerva Neurosciences
  • Class Antidepressants; Ketones; Pyrimidines; Pyrroles; Sleep disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Insomnia; Major depressive disorder

Most Recent Events

  • 11 Apr 2018 Janssen Research & Development plans a phase I trial for Healthy volunteers in Belgium , (NCT03494907)
  • 09 Feb 2018 Janssen Research & Development initiates enrolment in a phase I trial in USA (PO) (NCT03438461)
  • 02 Feb 2018 Janssen Research & Development terminates a phase II trial in Major depressive disorder (Adjunctive treatment, Treatment-experienced) in USA (PO), due to investigational product packaging issue (NCT03321526)
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