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Seltorexant - Janssen Research & Development/Minerva Neurosciences

Drug Profile

Seltorexant - Janssen Research & Development/Minerva Neurosciences

Alternative Names: JNJ-42847922; JNJ-7922; MIN-202

Latest Information Update: 10 May 2022

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At a glance

  • Originator Janssen Research & Development
  • Developer Janssen Research & Development; Minerva Neurosciences
  • Class Antidepressants; Fluorinated hydrocarbons; Ketones; Pyrimidines; Pyrroles; Sleep disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Major depressive disorder
  • Phase II Alzheimer's disease; Insomnia
  • No development reported Sleep apnoea syndrome

Most Recent Events

  • 06 May 2022 Phase-II clinical trials in Alzheimer's disease (In adults, In the elderly) in USA (PO) (NCT05307692)
  • 25 Mar 2022 Janssen Research & Development plans a phase II trial in Alzheimer's Disease (In adults, In the elderly)(PO, Tablet), In USA and Ukraine, in March 2022 (NCT05307692)
  • 01 Mar 2022 Janssen Research & Development completes enrolment in a phase I trial (In volunteers) in Netherlands (IV) (NCT05236868)
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