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Prabotulinumtoxin A - Daewoong Pharmaceuticals

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Drug Profile

Prabotulinumtoxin A - Daewoong Pharmaceuticals

Alternative Names: ABP 450; DWP-450; Evosyal; Jeuveau; Nabota; Nuceiva; Onabotulinumtoxin A biosimilar - Daewoong Pharmaceuticals; Prabotulinumtoxin A; PrabotulinumtoxinA-xvfs

Latest Information Update: 29 Jan 2026

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At a glance

  • Originator Daewoong Pharmaceutical
  • Developer AEON Biopharma; Daewoong Pharmaceutical; Evolus
  • Class Analgesics; Anti-inflammatories; Antiarrhythmics; Antidepressants; Antimigraines; Antipruritics; Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Eye disorder therapies; Foot disorder therapies; Muscle relaxants; Recombinant proteins; Skin disorder therapies; Urologics; Vascular disorder therapies
  • Mechanism of Action Acetylcholine inhibitors; Glutamate antagonists; Membrane transport protein modulators; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Glabellar lines
  • Phase III Hypertrophy; Muscle spasticity; Torticollis
  • Phase II/III Blepharospasm; Facial wrinkles
  • Phase II Migraine
  • Phase I Gastroparesis
  • Preclinical Post-traumatic stress disorders

Most Recent Events

  • 21 Jan 2026 AEON Biopharma reports BPD Type 2a meeting with FDA in line with prior guidance, and awaits official meeting minutes
  • 20 Nov 2025 The US FDA plans to conduct a biosimilar biological product development (BPD) type 2a meeting with AEON Biopharma on January 21, 2026
  • 09 Jul 2025 Launched for Glabellar lines in France (IM)

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