Prabotulinumtoxin A - Daewoong Pharmaceuticals

Drug Profile

Prabotulinumtoxin A - Daewoong Pharmaceuticals

Alternative Names: DWP-450; Evosyal; Nabota; Prabotulinumtoxin A

Latest Information Update: 21 Feb 2018

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At a glance

  • Originator Daewoong Pharmaceutical
  • Developer ALPHAEON Corporation; Daewoong Pharmaceutical
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants
  • Mechanism of Action Acetylcholine inhibitors; Glutamate-antagonists; Membrane transport protein modulators; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Glabellar lines
  • Phase III Muscle spasticity
  • Phase II/III Blepharospasm; Facial-wrinkles

Most Recent Events

  • 17 Feb 2018 European - Canadian comparative adverse events and efficacy data from the phase III EVB-003 trial in Glabellar lines released by Evolus
  • 14 Dec 2017 Daewoong Pharmaceutical plans the randomised, double-blind, placebo-controlled phase II optimal dose-finding trial for benign masseteric Hypertrophy, in December 2017 , (NCT03369990)
  • 26 Oct 2017 Preregistration for Glabellar lines in Canada (Parenteral)
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