Belantamab mafodotin - GSK
Alternative Names: anti-BCMA-ADC - GSK ; Belamaf; belantamab mafodotin-blmf; blenrep; BLENREP; GSK'916; GSK-2857916; J6M0-mcMMAFLatest Information Update: 27 Aug 2026
At a glance
- Originator GlaxoSmithKline
- Developer Amgen; Atrium Health; GSK
- Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
- Mechanism of Action Tubulin polymerisation inhibitors
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Orphan Drug Status
Yes - Multiple myeloma
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Registered Multiple myeloma
- Phase I/II Amyloid light-chain amyloidosis
Most Recent Events
- 19 Aug 2026 Registered for Multiple myeloma (Combination therapy, Second-line therapy or greater) in Singapore (IV)
- 15 Jun 2026 GSK plans the phase II REBEL trial for Multiple myeloma (Combination therapy, Late-stage disease, Second-line therapy or greater) in Poland (IV), in June 2026 (CTIS2025-525096-83-00) (EUCT2025-525096-83-00)
- 02 Jun 2026 Efficacy and adverse event data from a phase I/II trial in Multiple myeloma presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)