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Belantamab mafodotin - GSK

Drug Profile

Belantamab mafodotin - GSK

Alternative Names: anti-BCMA-ADC - GSK ; Belamaf; belantamab mafodotin-blmf; blenrep; BLENREP; GSK'916; GSK-2857916; J6M0-mcMMAF

Latest Information Update: 12 Jun 2024

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At a glance

  • Originator GlaxoSmithKline
  • Developer Amgen; Atrium Health; GSK
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Multiple myeloma
  • Phase II Plasmablastic lymphoma

Most Recent Events

  • 07 Jun 2024 Efficacy and adverse events data from a phase III DREAMM-7 trial in multiple melanoma released by GlaxoSmithKline
  • 03 Jun 2024 Efficacy and adverse events data from a phase III DREAMM 8 trial in Multiple myeloma released by GSK
  • 29 Feb 2024 GlaxoSmithKline completes the phase II trial in Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA, France, United Kingdom, Australia, Spain and Canada (IV) (NCT03544281)
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