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RG 101

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Drug Profile

RG 101

Alternative Names: RG-101; RG-101Rx

Latest Information Update: 01 Jul 2025

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At a glance

  • Originator Stanford University
  • Developer Novartis
  • Class Antisense oligonucleotides; Antivirals; MicroRNAs
  • Mechanism of Action MIRN122 microRNA inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis C

Most Recent Events

  • 25 Jun 2025 Regulus Therapeutics has been acquired and merged into Novartis
  • 08 Sep 2021 Regulus and GlaxoSmithKline completed a phase II trial in chronic Hepatitis C
  • 01 Aug 2017 Discontinued - Phase-I for Hepatitis C in USA, Netherlands (SC) before August 2017

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