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Mitoxantrone liposomal - CSPC ZhongQi Pharmaceutical Technology

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Drug Profile

Mitoxantrone liposomal - CSPC ZhongQi Pharmaceutical Technology

Alternative Names: 2010L04017; Duoenda; Mitoxantrone hydrochloride liposome; Pegylated liposomal mitoxantrone; PLM-60

Latest Information Update: 12 Aug 2024

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At a glance

  • Originator CSPC ZhongQi Pharmaceutical Technology
  • Developer CSPC ZhongQi Pharmaceutical Technology; Huizhou Municipal Central Hospital; Jinhua Central Hospital; Ningbo No. 1 Hospital; The Second Affiliated Hospital of Zhejiang University School of Medicine
  • Class Amines; Anthraquinones; Antineoplastics; Small molecules
  • Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Registered Peripheral T-cell lymphoma
  • Phase II Breast cancer; Cutaneous T-cell lymphoma; Diffuse large B cell lymphoma; Neuromyelitis optica; Small cell lung cancer; Solid tumours
  • Phase I/II Extranodal NK-T-cell lymphoma; Immunoblastic lymphadenopathy; Non-Hodgkin's lymphoma
  • Phase I Gastric cancer; Head and neck cancer; Multiple myeloma; Oesophageal cancer; Ovarian cancer; Soft tissue sarcoma
  • Clinical Phase Unknown Liver cancer

Most Recent Events

  • 18 Jul 2024 CSPC ZhongQi Pharmaceutical Technology completes a Phase-II clinical trials in Neuromyelitis optica in China (IV) (NCT05551598)
  • 23 Feb 2024 CSPC ZhongQi Pharmaceutical Technology terminates a phase-II trial in Breast cancer (In adults, In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in China (IV) as the sponsor had adjusted its R&D strategy (NCT04927481)
  • 21 Feb 2024 Mitoxantrone liposomal is still in phase II trials for Diffuse large B-cell lymphoma in China (NCT05875428)

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