Mitoxantrone liposomal - CSPC ZhongQi Pharmaceutical Technology
Alternative Names: 2010L04017; Duoenda; Mitoxantrone hydrochloride liposome; Pegylated liposomal mitoxantrone; PLM-60Latest Information Update: 12 Aug 2024
At a glance
- Originator CSPC ZhongQi Pharmaceutical Technology
- Developer CSPC ZhongQi Pharmaceutical Technology; Huizhou Municipal Central Hospital; Jinhua Central Hospital; Ningbo No. 1 Hospital; The Second Affiliated Hospital of Zhejiang University School of Medicine
- Class Amines; Anthraquinones; Antineoplastics; Small molecules
- Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Registered Peripheral T-cell lymphoma
- Phase II Breast cancer; Cutaneous T-cell lymphoma; Diffuse large B cell lymphoma; Neuromyelitis optica; Small cell lung cancer; Solid tumours
- Phase I/II Extranodal NK-T-cell lymphoma; Immunoblastic lymphadenopathy; Non-Hodgkin's lymphoma
- Phase I Gastric cancer; Head and neck cancer; Multiple myeloma; Oesophageal cancer; Ovarian cancer; Soft tissue sarcoma
- Clinical Phase Unknown Liver cancer
Most Recent Events
- 18 Jul 2024 CSPC ZhongQi Pharmaceutical Technology completes a Phase-II clinical trials in Neuromyelitis optica in China (IV) (NCT05551598)
- 23 Feb 2024 CSPC ZhongQi Pharmaceutical Technology terminates a phase-II trial in Breast cancer (In adults, In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in China (IV) as the sponsor had adjusted its R&D strategy (NCT04927481)
- 21 Feb 2024 Mitoxantrone liposomal is still in phase II trials for Diffuse large B-cell lymphoma in China (NCT05875428)