Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Adrabetadex - Mandos/National Institutes of Health

Next Previous
Search
Drug Profile

Adrabetadex - Mandos/National Institutes of Health

Alternative Names: 2-Hydroxypropyl-B-Cyclodextrin - Mandos; 2-Hydroxypropyl-beta-cyclodextrin - Mandos; HP-beta-CD - Mandos; HPBCD - Mandos; Hydroxypropyl betadex - Mandos; Hydroxypropyl betadex intrathecal - Mandos; Intrathecal hydroxypropyl betadex - Mandos; IT-HPBCD - Mandos; VTS 270

Latest Information Update: 28 Sep 2023

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator National Institutes of Health (USA)
  • Developer Mallinckrodt plc; Mandos; National Institute of Child Health and Human Development; Washington University School of Medicine
  • Class Antidementias; Beta-Cyclodextrins; Ethers
  • Mechanism of Action Binding agents; Cholesterol modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Niemann-Pick disease type C
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Niemann-Pick disease type C

Most Recent Events

  • 28 Sep 2023 Chemical structure information added
  • 14 Apr 2022 Mandos terminates a phase II/III trial in Niemann-Pick disease type C (In children, In adolescents, In adults) in Australia, France, Germany, Italy, New Zealand, Singapore, Spain, Turkey, United Kingdom and USA (Intrathecal) (NCT02534844) (EudraCT2015-002548-15)
  • 14 Apr 2022 Mandos terminates a Phase-II/III clinical trial in Niemann-Pick disease type C (In adolescents, In children, In adults) in Costa Rica (Intrathecal), due to previous sponsor's decision (NCT03879655)

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:
  • Contacting your organization’s admin about adding this content to your AdisInsight subscription
  • Buying a PDF version of any individual profile
  • Request a free trial
If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top