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Fulacimstat - Bayer Healthcare

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Drug Profile

Fulacimstat - Bayer Healthcare

Alternative Names: BAY 1142524

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Bayer HealthCare
  • Class Antihypoglycaemics; Benzoxazoles; Heart failure therapies; Pyrimidines; Small molecules; Urologics
  • Mechanism of Action Chymase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Kidney disorders; Left ventricular dysfunction; Type 2 diabetes mellitus

Most Recent Events

  • 28 Mar 2021 No recent reports of development identified for phase-I development in Kidney-disorders in Germany (PO, Tablet)
  • 02 Oct 2019 Bayer completes a phase II trial in Kidney disorders and Type 2 diabetes mellitus in Bulgaria, Denmark, Finland, Israel, Italy, Spain and Sweden (PO, Tablet) (NCT03412006)
  • 31 Aug 2019 Adverse events data from a phase IIa CHIARA MIA 2 trial in patients with reduced Left ventricular ejection fraction after acute myocardial infarction presented at the Annual Congress of the European Society of Cardiology (ESC-2019)

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